nicotinamide riboside supplement side effects on the human body

Have scientists finally discovered the fountain of youth? That’s what many people hope, and maybe we are a step closer. It seems researchers have found a way to protect age related DNA damage in mice. The researchers focused on a compound called NAD+ with unique anti-aging properties, they discovered when they increased NAD+ (nicotinamide adenine dinucleotide) levels in older mice they appeared to look biologically like much younger mice, “We can’t tell the difference between the tissues from an old mouse that is two years old versus a young mouse that is three to four months old,” one researcher said.

 Obviously this has lead to the question, “will this work for people?” and a number of products and supplements have emerged to capitalize on this new discovery. One of the supplements that has increased in popularity is Nicotinamide Riboside or NR for short. Nicotinamide Riboside is a recently discovered form of vitamin B3 that has been proven to increase NAD+ levels in Humans.

 Now this is all exciting news! So you might be asking yourself, well there must be a catch? Are there any negative side effects? As with any supplement, it’s important to be aware of what possible adverse reactions may result from taking them, so you can be on guard for if and when they arise. As far as nicotinamide riboside side effects are concerned, much of the findings are said to be quite positive.

 Side effects:Nicotinamide Riboside was not found to be genotoxic.

 Nicotinamide Riboside’s toxicity and side effects were found to be similar to regular nicotinamide. In fact studies of the supplement have found no noticeable side effects of dosages up to 3,000mg per day. One of the key features of using NR is that people don’t seem to experience unpleasant flushing caused with niacin.


 We know from human studies that NR at a bare minimum has been proven to

  •  Protect individuals from hearing damage
  • Increase NAD+ levels.

And we know from studies in Mice that increased NAD+ levels have the potential to

  •  Improve cardiovascular health
  • Improve energy levels
  • Decrease muscle soreness
  • Improve memory
  • Improve sleep
  • Improve hearing and vision

It’s important to remember that the most of studies conducted so far have been on  animal models taking high dosages. It’s fair to say that we all know, not everything that works well in mice or even rhesus monkeys is going to necessarily translate to human beings. However,with that said, it appears as though the hype –at least for now – is justified, given the numerous promising studies so far suggesting Nicotinamide Riboside’s ability to increase NAD+ levels.




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